SnapShot: Melanoma

SnapShot: melanoma.

SnapShot: Macroautophagy

(Middle) Cellular Events in Macroautophagy Macroautophagy (hereafter referred to as autophagy) is a catabolic process in which portions of the cytoplasm are sequestered within double-or multimembraned vesicles termed autophagosomes and then delivered to lysosomes for bulk degradation. The initial phases of macroautophagy consist of the formation of a phago-phore, which is also called an isolati...

SnapShot: Formins

See online version for legend and references. Autosomal-dominant nonsyndromic deafness (DFNA1), myeloproliferative defects, defects in T lymphocyte traffi cking and proliferation, tumor cell invasion, defects in natural killer lymphocyte function DIAPH2 (mDia3) Cdc42 Kinetochore Stable microtubule attachment to kinetochore for chromosome alignment Premature ovarian failure DIAPH3 (mDia2) Increa...

SnapShot: Inflammasomes

SnapShot: Hematopoiesis